Janson C, Gislason T, De Backer W, Plaschke P, Björnsson E, Hetta J, Kristbjarnason H, Vermeire P, Boman G
Department of Lung Medicine, Akademiska sjukhuset, Uppsala, Sweden.
Sleep. 1995 Sep;18(7):589-97.
The aim of this investigation was to study the geographic variation in sleep complaints and to identify risk factors for sleep disturbances in three European countries: Iceland (Reykjavik), Sweden (Uppsala and Göteborg) and Belgium (Antwerp). The study involved a random population of 2,202 subjects (age 20-45 years) who participated in the European Community Respiratory Health Survey. The subjects answered a questionnaire on sleep disturbances. Participants in Iceland and Sweden also estimated their sleep habits and sleep times during a period of 1 week in a sleep diary. Habitual (> or = 3/week) difficulties inducing sleep (DIS) were reported by 6-9% and early morning awakenings by 5-6% of the subjects. The estimated number of awakenings and the prevalence of nightmares was significantly lower in Reykjavik. Participants in Reykjavik went to bed at night and woke in the morning approximately 1 hour later than participants at the Swedish centers (p < 0.001). Symptoms of gastroesophageal reflux (GER) were associated with DIS (odds ratio [OR] = 2.7), nightmares (OR = 4.4), longer sleep latency and frequent nocturnal awakenings. Smoking correlated positively to DIS (OR = 1.8) and estimated sleep latency. We conclude that the prevalence of DIS was fairly similar at these four European centers but that there was a variation in the prevalence of nightmares and nocturnal awakenings. The significant correlation between reported GER and subjective quality of sleep should be followed up in studies using objective measurements.
本调查的目的是研究三个欧洲国家(冰岛雷克雅未克、瑞典乌普萨拉和哥德堡、比利时安特卫普)睡眠问题的地域差异,并确定睡眠障碍的风险因素。该研究纳入了参与欧洲共同体呼吸健康调查的2202名年龄在20至45岁之间的随机人群。受试者回答了一份关于睡眠障碍的问卷。冰岛和瑞典的参与者还在睡眠日记中记录了他们在1周内的睡眠习惯和睡眠时间。6%至9%的受试者报告有习惯性(每周≥3次)入睡困难(DIS),5%至6%的受试者报告有早醒情况。雷克雅未克的受试者夜间觉醒次数估计值和噩梦发生率显著较低。雷克雅未克的参与者晚上上床睡觉和早上醒来的时间比瑞典各中心的参与者大约晚1小时(p<0.001)。胃食管反流(GER)症状与DIS(比值比[OR]=2.7)、噩梦(OR=4.4)、较长的睡眠潜伏期和频繁的夜间觉醒有关。吸烟与DIS(OR=1.8)和估计的睡眠潜伏期呈正相关。我们得出结论,这四个欧洲中心的DIS患病率相当相似,但噩梦和夜间觉醒的患病率存在差异。GER与主观睡眠质量之间的显著相关性应在使用客观测量的研究中进一步跟进。