Gugger M, Mathis J, Bassetti C
Department of Medicine, University of Berne, Inselspital, Switzerland.
Thorax. 1995 Nov;50(11):1199-201. doi: 10.1136/thx.50.11.1199.
In patients with sleep apnoea early diagnostic evaluation and treatment may be delayed due to limited access to full polysomnography (PSG). For "typical" patients, simplified strategies are needed. A study was performed to evaluate the accuracy of a new continuous positive airway pressure (CPAP) device with in-built diagnostic abilities (Autoset) in detecting apnoeas.
Twenty seven patients underwent full overnight polysomnography. Data with the Autoset were acquired simultaneously. Standard nasal prongs were used. Apnoeas were detected by special analysis of the flow signal. As the Autoset derives all its data from one signal, careful examination of the raw data is important to assess the quality of the flow signal.
There was a correlation between the apnoea index (AI) assessed by the Autoset (AI-Autoset) and by polysomnography AI-PSG (r = 0.85) and between the AI-Autoset and the apnoea/hypopnoea index (AHI) during polysomnography (r = 0.87). The Autoset identified patients with an AHI-PSG of > 20 (a level of respiratory disturbance that would warrant consideration for treatment in most centres for sleep disorders) with a sensitivity of 82% and a specificity of 90%.
The good correlation between the apnoea index measured by the Autoset and by polysomnography, and the high sensitivity in detecting patients with an AHI of > 20, may make the Autoset a valuable tool for the management of typical patients with sleep apnoea. However, very low values for nasal ventilation on the printout raises the suspicion of poor signal quality and misleading results.
在睡眠呼吸暂停患者中,由于全面多导睡眠图(PSG)检查受限,早期诊断评估和治疗可能会延迟。对于“典型”患者,需要简化策略。本研究旨在评估一种具有内置诊断功能的新型持续气道正压通气(CPAP)设备(自动调压型)检测呼吸暂停的准确性。
27例患者接受了整夜的全面多导睡眠图检查。同时采集自动调压型设备的数据。使用标准鼻导管。通过对流量信号进行特殊分析来检测呼吸暂停。由于自动调压型设备从一个信号获取所有数据,仔细检查原始数据对于评估流量信号质量很重要。
自动调压型设备评估的呼吸暂停指数(AI-Autoset)与多导睡眠图评估的AI-PSG之间存在相关性(r = 0.85),自动调压型设备评估的AI-Autoset与多导睡眠图期间的呼吸暂停/低通气指数(AHI)之间存在相关性(r = 0.87)。自动调压型设备识别出多导睡眠图AHI-PSG>20(在大多数睡眠障碍中心,这一呼吸紊乱水平需要考虑进行治疗)的患者,其敏感性为82%,特异性为90%。
自动调压型设备测量的呼吸暂停指数与多导睡眠图测量的结果之间具有良好的相关性,且在检测AHI>20的患者时具有较高的敏感性,这可能使自动调压型设备成为管理典型睡眠呼吸暂停患者的有价值工具。然而,打印输出的鼻通气值非常低会引发对信号质量差和结果误导的怀疑。