Bradley P A, Mortimore I L, Douglas N J
Department of Medicine, Royal Infirmary, Edinburgh, UK.
Thorax. 1995 Nov;50(11):1201-3. doi: 10.1136/thx.50.11.1201.
Increasing referral numbers make the development of simplified accurate methods of diagnosing the sleep apnoea/hypopnoea syndrome highly desirable. The accuracy of one such system--the ResCare Autoset--has been examined.
Thirty one consecutive patients assessed by polysomnography had simultaneous monitoring of their respiratory pattern using the Autoset system. The Autoset detects episodes of flattening of the flow/time profile using nasal cannulae.
There was a good correlation (r = 0.85) between the number of apnoeas+hypopnoeas/hour in bed recorded using polysomnography and the Autoset system. The median difference in such events was 3.1 (95% confidence interval 8.4 to -1.6)/hour in bed. In two patients the Autoset scored 70 apnoeas+hypopnoeas/hour in bed compared with 34 apnoeas+hypopnoeas with 35 arousals/hour in bed by polysomnography; however, this did not alter the diagnostic category of either patient. Autoset gave a sensitivity of 100%, specificity of 92%, positive predictive value of 92%, and negative predictive value of 100%, which was better than oximetry alone. A sleep study using the Autoset system costs 14 pounds compared with 126 pounds for polysomnography.
The Autoset is clinically useful for diagnosing the sleep apnoea/hypopnoea syndrome.
转诊人数不断增加,使得开发简化且准确的睡眠呼吸暂停/低通气综合征诊断方法变得极为必要。已对其中一种系统——ResCare Autoset的准确性进行了研究。
通过多导睡眠图评估的31例连续患者使用Autoset系统同时监测其呼吸模式。Autoset通过鼻导管检测流量/时间曲线变平的发作情况。
多导睡眠图记录的每小时卧床呼吸暂停+低通气次数与Autoset系统之间存在良好的相关性(r = 0.85)。此类事件的中位数差异为每小时卧床3.1次(95%置信区间为8.4至-1.6次)。在两名患者中,Autoset记录的每小时卧床呼吸暂停+低通气次数为70次,而多导睡眠图显示每小时有34次呼吸暂停+低通气以及35次觉醒;然而,这并未改变任何一名患者的诊断类别。Autoset的敏感性为100%,特异性为92%,阳性预测值为92%,阴性预测值为100%,优于单独使用脉搏血氧饱和度测定法。使用Autoset系统进行睡眠研究的费用为14英镑,而多导睡眠图的费用为l26英镑。
Autoset在临床上对诊断睡眠呼吸暂停/低通气综合征有用。