Edmond M B, Wenzel R P, Pasculle A W
Medical College of Virginia, Richmond, USA.
Ann Intern Med. 1996 Feb 1;124(3):329-34. doi: 10.7326/0003-4819-124-3-199602010-00008.
Given the dramatic increase in the incidence of vancomycin resistance among the enterococci and experimental evidence for the transfer of vancomycin resistance from enterococci to Staphylococcus aureus, there is concern that strains of S. aureus will emerge that are resistant to vancomycin. The result would be a highly virulent pathogen for which effective antimicrobial therapy would not be available. To prevent the nosocomial transmission of such an organism, stringent infection control policies need to be developed and implemented. We offer proposals that are based on the limited data available on the transmission and control of S. aureus and that may be used as starting points for the development of formal guidelines for the isolation of colonized and infected patients and for microbiology laboratory precautions.
鉴于肠球菌中万古霉素耐药性的发生率急剧上升，以及有实验证据表明万古霉素耐药性可从肠球菌转移至金黄色葡萄球菌，人们担心会出现对万古霉素耐药的金黄色葡萄球菌菌株。这将产生一种高毒力病原体，而目前尚无有效的抗菌治疗方法。为防止此类病原体在医院内传播，需要制定并实施严格的感染控制政策。我们根据关于金黄色葡萄球菌传播和控制的有限数据提出建议，这些建议可作为制定针对定植和感染患者隔离以及微生物实验室预防措施的正式指南的起点。
