Kret B, Milad M, Jeyendran R S
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois, USA.
Arch Androl. 1995 Jul-Aug;35(1):29-33. doi: 10.3109/01485019508987850.
Neutral alpha-glucosidase activity was measured in seminal plasma of 30 patients consulting for infertility with a variety of disorders, and compared with 25 normal controls. Significantly more of the study populations (asthenozoospermia, 4/6; oligozoospermia, 3/5; azoospermia 8/15) had a neutral alpha-glucosidase activity less than 10 mIU/mL as compared with control samples (3/25). Also the mean (+/- SD) neutral alpha-glucosidase activity in patients with asthenozoospermia (11.7 +/- 9.2) oligozoospermia (11.3 +/- 7.2), and post vasectomy azoospermia (5.3 +/- 3.4) was significantly (p < .05) less than ejaculate from controls (21.2 +/- 14). A seminal alpha-glucosidase level of 10 mIU/mL appears to be a useful discriminatory marker in the diagnosis of epididymal obstruction or dysfunction.
对30名因各种病症前来咨询不孕问题的患者的精浆进行了中性α-葡萄糖苷酶活性检测，并与25名正常对照者进行了比较。与对照样本（3/25）相比，研究人群中（弱精子症患者4/6；少精子症患者3/5；无精子症患者8/15）中性α-葡萄糖苷酶活性低于10 mIU/mL的人数明显更多。此外，弱精子症患者（11.7±9.2）、少精子症患者（11.3±7.2）和输精管结扎术后无精子症患者（5.3±3.4）的平均（±标准差）中性α-葡萄糖苷酶活性显著（p<0.05）低于对照组的射精样本（21.2±14）。精浆α-葡萄糖苷酶水平为10 mIU/mL似乎是诊断附睾梗阻或功能障碍的一个有用的鉴别标志物。
