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[癫痫样病灶电导率变化在阵发性活动扩散中的作用]

[Role of a change in the electric conductivity of an epileptiform focus in the spread of paroxysmal activity].

作者信息

Belenkov N Iu, Chirkov V D, Syzganov A I

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 Jan-Feb;27(1):137-46.

PMID:855478
Abstract

In acute experiments on unanaesthetized cats a study was made of the influence of shunting a region of the cortex with a metal plate on its electrical activity and impedance. Shunting of a region of strychninization reduces the amplitude of paroxysmal oscillations in the focus and in remote regions of the cortex, reduces their frequency and produces a considerable lowering of the impedance both in the regions of the cortex between the active electrodes and between active and indifferent electrodes. Impedance of the strychninized cortex is lower than the total resistance of the intact neocortex; this testifies to the rise of conductivity in the area of strychninization, which is similar to application of a shunting plate. The data obtained corroborate the substantial role of the bioelectrical field in the development of electroencephalographic paroxysmal manifestations.

摘要

在对未麻醉猫进行的急性实验中,研究了用金属板分流大脑皮层某区域对其电活动和阻抗的影响。士的宁化区域的分流降低了皮层病灶及皮层远端区域阵发性振荡的幅度,降低了其频率,并使活动电极之间以及活动电极与无关电极之间的皮层区域阻抗显著降低。士的宁化皮层的阻抗低于完整新皮层的总电阻;这证明了士的宁化区域电导率的升高,这类似于应用分流板。所获得的数据证实了生物电场在脑电图阵发性表现发展中的重要作用。

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1
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