[雾化对鼠疫活菌苗生物学特性的影响]
[Effect of aerosolization on the biological properties of live plague vaccine].
作者信息
Evstigneev V I, Chicherin Iu V, Lebedinskiĭ V A
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1977 Feb(2):108-11.
PMID:855516
Abstract
The authors present the results of experiments on the study of the influence of aerozolation on the biological properties of the microbes of live plaque vaccine. It appeared that its aerozol condition for a period of 10 minutes had no effect on the residual virulence of the microbes, but for a period of 30 minutes--led to an 8-fold fall of the virulence. The immunogenic activity of the live microbes of the vaccine kept at the state of "static" and "dynamic aerozol" for a period of 5 minutes was unchanged.
摘要
作者展示了关于气雾化对活菌斑疫苗微生物生物学特性影响的实验结果。结果显示，其气雾化状态持续10分钟对微生物的残余毒力没有影响，但持续30分钟会导致毒力下降8倍。疫苗活微生物在“静态”和“动态气雾化”状态下保持5分钟，其免疫原活性未发生变化。
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