Chicherin Iu V, Evstigneev V I, Lebedinskiĭ V A
Zh Mikrobiol Epidemiol Immunobiol. 1977 Apr(4):97-8.
The authors present the results of experimental studies on guinea pigs of the dynamics of plague immunity formation after a single inhalation immunization of the animals with live plague vaccine. Plague immunity proved to develop as soon as 24 hours after the application of the preparation; by the 3rd day the resistance level was 68 times greater than the control one. Immunity reached the maximal intensity by the 20th day after the vaccination. The level of specific resistance decreased 1.6 by the 3rd month.
作者介绍了豚鼠单次吸入活鼠疫疫苗免疫后鼠疫免疫形成动力学的实验研究结果。结果表明，在接种制剂后24小时鼠疫免疫力就开始形成；到第3天，抵抗力水平比对照组高68倍。免疫在接种后第20天达到最大强度。到第3个月时，特异性抵抗力水平下降了1.6倍。
