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墨西哥城高碳水化合物摄入量人群的颈动脉粥样硬化

Carotid artery atherosclerosis in a Mexico City population with high carbohydrate intake.

作者信息

González-Villalpando C, Stern M P, Rivera Martínez D, Arredondo Pérez B, Martínez Diaz S, Haffner S

机构信息

Centro de Estudios en Diabetes, American British Cowdray Hospital, México, D.F.

出版信息

Arch Med Res. 1995 Winter;26(4):409-13.

PMID:8555736
Abstract

We present the results of a population based survey designed to estimate the prevalence and clinical characteristics of carotid artery atherosclerosis (CAS) diagnosed using vascular ultrasonography (VUS) in a low income area of Mexico City encompassing six neighborhoods that we previously studied. We attempted to locate all the non-diabetic participants of the first two neighborhoods (n = 834) and all diabetics from the six neighborhoods (n = 304). We located 1078 (94.7%) participants and examined 770 (71.4%). All study subjects were men and non-pregnant women between 35-64 years of age and had standardized VUS protocol. In men, the prevalence of CAS was 16.29%, in women the prevalence was 12.3%. CAS was significantly associated in both sexes to age (p < 0.001) and systolic blood pressure (p < 0.001). The ratio of the subscapular to triceps skinfolds was significantly higher in men with CAS (p < 0.04). In women, fasting glucose was higher in subjects with CAS (p < 0.04). The lipid profile was similar in men with and without CAS. However, women with CAS had significantly higher total cholesterol (p < 0.001), LDL cholesterol (p < 0.002), VLDL cholesterol (p < 0.092) and mean TG (p < 0.033). The percent of patients with hypertension, tobacco use, myocardial infarction and diabetic retinopathy of any degree was significantly higher in the subjects with CAS. CAS of any degree was observed in 12.4% of the non-diabetic population and 18.13% of the diabetics.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们展示了一项基于人群的调查结果,该调查旨在估计在墨西哥城一个低收入地区,使用血管超声检查(VUS)诊断的颈动脉粥样硬化(CAS)的患病率和临床特征,该地区涵盖我们之前研究过的六个社区。我们试图找到前两个社区的所有非糖尿病参与者(n = 834)以及六个社区的所有糖尿病患者(n = 304)。我们找到了1078名参与者(94.7%),并对770名(71.4%)进行了检查。所有研究对象均为35至64岁的男性和非孕妇,且有标准化的VUS检查方案。男性中,CAS的患病率为16.29%,女性患病率为12.3%。CAS在男女两性中均与年龄(p < 0.001)和收缩压(p < 0.001)显著相关。CAS男性的肩胛下与肱三头肌皮褶厚度之比显著更高(p < 0.04)。在女性中,CAS患者的空腹血糖更高(p < 0.04)。有和没有CAS的男性血脂谱相似。然而,患有CAS的女性总胆固醇(p < 0.001)、低密度脂蛋白胆固醇(p < 0.002)、极低密度脂蛋白胆固醇(p < 0.092)和平均甘油三酯(p < 0.033)显著更高。患有高血压、吸烟、心肌梗死和任何程度糖尿病视网膜病变的患者百分比在患有CAS的受试者中显著更高。在非糖尿病人群中,12.4%的人观察到有任何程度的CAS,糖尿病患者中这一比例为18.13%。(摘要截选至250字)

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