Akoua-Koffi G, Thonnon J, Kouassi-Renaud M, Dosso M, Ehouman A
Institut Pasteur de Côte d'Ivoire.
Bull Soc Pathol Exot. 1995;88(3):117-20.
In order to determine the antipoliomyelitis seroprevalence of children in Abidjan, we checked the presence of antipoliovirus antibodies in 48 children received in the South Abobo's vaccination center for vaccination against measles. According to the vaccination schedule and rules applied in Côte d'Ivoire: 12.5% of the children have received less than three doses or oral polio vaccine (OPV), 87.5% have received the three doses. Antibody titration results indicated that 78.6, 93 and 76.2% of the children have been immunized against Poliovirus type I, type II and type III, respectively; 71.4% of the children showed antibodies against the three poliovirus serotypes and 4.8% had no antipoliovirus antibodies at all. The children which showed an antibodies titer less than 1/8 were considered unprotected: the proportion of unprotected was 21.4, 7 and 23.8% against Poliovirus type I, type II and type III, respectively. Although these results showed that the level of protection against poliomyelitis in Abidjan is acceptable (> 75%), the efforts for vaccination program in Côte d'Ivoire need to be improved in order to eradicate poliomyelitis.
为了确定阿比让儿童的抗脊髓灰质炎血清流行率,我们检测了在南阿博博疫苗接种中心接受麻疹疫苗接种的48名儿童体内抗脊髓灰质炎病毒抗体的存在情况。根据科特迪瓦应用的疫苗接种计划和规则:12.5%的儿童接种的口服脊髓灰质炎疫苗(OPV)少于三剂,87.5%的儿童接种了三剂。抗体滴定结果表明,分别有78.6%、93%和76.2%的儿童已接种I型、II型和III型脊髓灰质炎病毒疫苗;71.4%的儿童显示出针对三种脊髓灰质炎病毒血清型的抗体,4.8%的儿童完全没有抗脊髓灰质炎病毒抗体。抗体滴度低于1/8的儿童被视为未得到保护:针对I型、II型和III型脊髓灰质炎病毒,未得到保护的比例分别为21.4%、7%和23.8%。尽管这些结果表明阿比让针对脊髓灰质炎的保护水平是可接受的(>75%),但为根除脊髓灰质炎,科特迪瓦的疫苗接种计划仍需改进。