Tobita Y, Otaki H, Kusaka Y, Iki M, Kajita E, Sato K
Fukui Industrial Health Center, Japan.
Sangyo Eiseigaku Zasshi. 1995 Nov;37(6):409-15. doi: 10.1539/sangyoeisei.37.6_409.
We examined the relationships between maximum oxygen uptake (Vo2max) and cardiovascular risk factors including age (year), systolic blood pressure (mmHg), diastolic blood pressure (mmHg), serum total cholesterol level (mg/dl), serum high-density lipoprotein level (mg/dl), serum triglyceride level (mg/dl), blood glucose level (mg/dl), serum uric acid level (mg/dl), body fat (%bw), Body Mass Index (BMI), alcohol (points/day), cigarettes (/day), and physical activity (METs.exercise time/30 days). The alcohol point was defined as follows: beer 633ml = a glass of whiskey and water - sake 180ml = 1 point, and totaled at 30 days. The subjects of our study were 162 males (aged 40.6 +/- 13.1) and 133 females (aged 41.3 +/- 11.1) who underwent medical and physical examinations at the Fukui Industrial Health Center from April, 1991 to June, 1992. As a result of simple correlation analysis in males, Vo2max had significantly negative correlations with age (r = -0.223, p < 0.01), systolic blood pressure (r = -0.228, p < 0.01), diastolic blood pressure (r = -0.239, p < 0.01), or serum triglyceride level (r = -0.258, p < 0.001), serum uric acid level (p < 0.05), body fat (r = -0.230, p < 0.01), and BMI (r = -0.312, p < 0.001), and was positively correlated with physical activity (r = -0.249, p < 0.01). On the other hand, in females, age (r = -0.224, p < 0.01), systolic blood pressure (r = -0.222, p < 0.01), diastolic blood pressure (r = -0.267, p < 0.01), serum triglyceride level (r = -0.261, p < 0.001), body fat (r = -0.280, p < 0.01), and BMI (r = -302, p < 0.001), had significantly negative correlations with VO2max. However, partial correlations were tested after controlling body fat, BMI, cigarette, alcohol, physical activity, and age, none of the factors correlated with VO2max significantly. These findings suggest that the risk factors for cardiovascular diseases are related to VO2max, and the life style has an influence on these correlations. Thus, VO2max may be a comprehensive indicator for health promotion among the working population. Furthermore a longitudinal study is required to determine whether the increase in VO2max is related to the improvement in the risk of cardiovascular diseases.
我们研究了最大摄氧量(Vo2max)与心血管危险因素之间的关系,这些危险因素包括年龄(岁)、收缩压(mmHg)、舒张压(mmHg)、血清总胆固醇水平(mg/dl)、血清高密度脂蛋白水平(mg/dl)、血清甘油三酯水平(mg/dl)、血糖水平(mg/dl)、血清尿酸水平(mg/dl)、体脂(%bw)、体重指数(BMI)、饮酒量(每天的点数)、吸烟量(每天的支数)以及身体活动量(代谢当量·运动时间/30天)。饮酒点数的定义如下:633毫升啤酒 = 一杯威士忌加水 = 180毫升清酒 = 1点,按30天累计计算。我们的研究对象是1991年4月至1992年6月期间在福井工业健康中心接受医学和身体检查的162名男性(年龄40.6±13.1岁)和133名女性(年龄41.3±11.1岁)。男性的简单相关分析结果显示,Vo2max与年龄(r = -0.223,p < 0.01)、收缩压(r = -0.228,p < 0.01)、舒张压(r = -0.239,p < 0.01)、血清甘油三酯水平(r = -0.258,p < 0.001)、血清尿酸水平(p < 0.05)、体脂(r = -0.230,p < 0.01)和BMI(r = -0.312,p < 0.001)呈显著负相关,与身体活动量呈正相关(r = -0.249,p < 0.01)。另一方面,在女性中,年龄(r = -0.224,p < 0.01)、收缩压(r = -0.222,p < 0.01)、舒张压(r = -0.267,p < 0.01)、血清甘油三酯水平(r = -0.261,p < 0.001)、体脂(r = -0.280,p < 0.01)和BMI(r = -302,p < 0.001)与VO2max呈显著负相关。然而,在控制了体脂、BMI、吸烟、饮酒、身体活动量和年龄后进行偏相关分析,这些因素均与VO2max无显著相关性。这些发现表明,心血管疾病的危险因素与VO2max有关,生活方式对这些相关性有影响。因此,VO2max可能是在职人群健康促进的一个综合指标。此外,需要进行纵向研究以确定VO2max的增加是否与心血管疾病风险的改善有关。