葡萄穗霉毒素，新型内皮素受体拮抗剂，由葡萄穗霉属菌株M6222产生。II. 葡萄穗霉毒素A、B和C的结构测定。
Stachybocins, novel endothelin receptor antagonists, produced by Stachybotrys sp. M6222. II. Structure determination of stachybocins A, B and C.
作者信息
Ogawa K, Nakamura M, Hayashi M, Yaginuma S, Yamamoto S, Furihata K, Shin-Ya K, Seta H
机构信息
Institute for Life Science Research, Asahi Chemical Industry Co. Ltd, Shizuoka, Japan.
出版信息
J Antibiot (Tokyo). 1995 Dec;48(12):1396-400. doi: 10.7164/antibiotics.48.1396.
The structures of stachybocins A, B and C, new endothelin receptor antagonist, were determined by NMR spectral analysis using pulse-field-gradient technique. Stachybocin A consists of two spirobenzofuran units each fused to a substituted decalin, which were connected by a lysine residue. Stachybocins B and C are derivatives of stachybocin A with an additional hydroxy group at the same position in the different decalin unit.
新型内皮素受体拮抗剂水苏糖素A、B和C的结构通过使用脉冲场梯度技术的核磁共振光谱分析得以确定。水苏糖素A由两个分别与一个取代十氢化萘稠合的螺苯并呋喃单元组成，这两个单元通过一个赖氨酸残基相连。水苏糖素B和C是水苏糖素A的衍生物，在不同十氢化萘单元的相同位置上有一个额外的羟基。
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