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Antimicrob Agents Chemother. 1977 Apr;11(4):760-2. doi: 10.1128/AAC.11.4.760.
2
The penetration of cefazolin, erythromycin and methicillin into human bone tissue.
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Cefazolin and cephalexin levels in prostatic tissue and sera.头孢唑林和头孢氨苄在前列腺组织及血清中的水平。
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Cefonicid concentrations in serum and atrial tissue during open-heart surgery.心脏直视手术期间血清和心房组织中的头孢尼西浓度。
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本文引用的文献

1
Experimental osteomyelitis. II. Therapeutic trials and measurement of antibiotic levels in bone.实验性骨髓炎。II. 治疗试验及骨中抗生素水平的测定
J Infect Dis. 1971 Dec;124(6):565-71. doi: 10.1093/infdis/124.6.565.
2
Experience with cefazolin: an overall summary of pharmacologic and clinical trials in man.头孢唑林的经验：人体药理学和临床试验的全面总结。
J Infect Dis. 1973 Oct;128:Suppl:S415-2. doi: 10.1093/infdis/128.supplement_2.s415.
3
Antibiotics in bone.
J Antimicrob Chemother. 1976 Sep;2(3):228-31. doi: 10.1093/jac/2.3.228.

头孢唑林钠在正常家兔血清、肌肉、骨髓和骨骼中的分布。

Distribution of sodium cefazolin in serum, muscle, bone marrow, and bone of normal rabbits.

作者信息

Pitkin D H, Sachs C, Zajac I, Actor P

出版信息

Antimicrob Agents Chemother. 1977 Apr;11(4):760-2. doi: 10.1128/AAC.11.4.760.

DOI:10.1128/AAC.11.4.760
PMID:856031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC352064/
Abstract

Cefazolin levels were detected in bone and bone marrow of normal rabbits dosed intramuscularly, even in the absence of detectable levels in serum.

摘要

在正常兔肌肉注射给药后，即便血清中未检测到可察觉的头孢唑林水平，但在其骨骼和骨髓中检测到了该药物水平。