Davies R H, Wray C
Bacteriology Department, Central Veterinary Laboratory, Addlestone, Surrey.
Vet Rec. 1995 Sep 30;137(14):337-41. doi: 10.1136/vr.137.14.337.
Evidence of the possible role of wild mice in the epidemiology of Salmonella enteritidis infection on broiler breeder and layer breeder units was obtained by a bacteriological examination of local mice. Persistent S enteritidis infection in birds on these units had been a problem and a high proportion of the mice were found to carry salmonella. S enteritidis was isolated from the liver and the intestine of most of the mice, indicating a systemic infection. Three-week-old chicks were infected by contact with droppings from mice which had been infected experimentally with S enteritidis two and five months previously. Wild mice infected artificially or naturally excreted S enteritidis intermittently, with up to 10(4) organisms in some individual droppings. A naturally infected mouse which died after intermittently excreting small numbers of S enteritidis in its droppings for 19 weeks had 10(4) organisms/g of liver and 10(3)/g of macerated intestine and contents. S enteritidis was also found in fetal tissue in a naturally infected mouse suggesting the possibility that the organism might be transmitted vertically.
通过对当地小鼠进行细菌学检查，获得了野生小鼠可能在肉种鸡和蛋种鸡场肠炎沙门氏菌感染流行病学中发挥作用的证据。这些鸡场的家禽持续感染肠炎沙门氏菌一直是个问题，并且发现很大比例的小鼠携带沙门氏菌。从大多数小鼠的肝脏和肠道中分离出肠炎沙门氏菌，表明存在全身感染。将3周龄的雏鸡与2个月和5个月前经实验感染肠炎沙门氏菌的小鼠粪便接触，雏鸡被感染。人工感染或自然感染的野生小鼠间歇性排出肠炎沙门氏菌，有些单个粪便中含有多达10⁴个菌体。一只自然感染的小鼠在其粪便中间歇性排出少量肠炎沙门氏菌19周后死亡，其肝脏中每克含有10⁴个菌体，捣碎的肠道及内容物中每克含有10³个菌体。在一只自然感染的小鼠的胎儿组织中也发现了肠炎沙门氏菌，这表明该菌可能存在垂直传播的可能性。
