Kadilov E V, Mugnetsian V A
Biull Eksp Biol Med. 1977 Jan;83(1):80-2.
Albino rats were subjected to multiple gravitation stress (11units) before infliction wounds. A marked vascular reaction was noted in the wound contents at the early observation period. The appearance and differentiation of granulation and epidermis proliferation periods were delayed. Healing the wound occurred on the 30th day (on the 15th--18th day in controls). Administration of the skin tissue extract (prepared by Filatory's method) under these conditions, simultaneously with the wound infliction and up to their healing sharply reduced the vascular reaction, accelerated the granulation differentiation and the epithelialization of the wound; in respect to the character and the periods of tissue differentiation development the restoration process thus approached the course of the post-traumatic skin regeneration under usual conditions.
白化大鼠在受伤前遭受多次重力应激（11单位）。在早期观察期，伤口内容物出现明显的血管反应。肉芽形成期和表皮增殖期的出现及分化延迟。伤口在第30天愈合（对照组在第15 - 18天愈合）。在这些条件下，在伤口造成时同时给予皮肤组织提取物（采用菲拉托里方法制备）直至伤口愈合，可显著减轻血管反应，加速肉芽分化和伤口上皮化；就组织分化发育的特征和时期而言，修复过程因此接近正常条件下创伤后皮肤再生的过程。
