Forrester T E, Wilks R J, Bennett F I, Simeon D, Osmond C, Allen M, Chung A P, Scott P
Tropical Metabolism Research Unit, University of the West Indies, Mona, Kingston, Jamaica.
BMJ. 1996 Jan 20;312(7024):156-60. doi: 10.1136/bmj.312.7024.156.
To determine relation between schoolchildren's blood pressure, glycated haemoglobin level, and cholesterol concentration and their anthropometry, socioeconomic status, and birth measurements.
Retrospective cohort study.
27 schools closest to University Hospital of the West Indies, Kingston, Jamaica.
2337 children aged 6-16 years who were born at university hospital were recruited, and their birth records were recovered: 1610 had suitable records, 659 had records including birth length, and 610 of these were prepubertal.
Blood pressure, glycated haemoglobin level, serum cholesterol concentration, anthropometry at birth, current anthropometry, and socioeconomic status.
Multiple regression analysis showed that children's systolic blood pressure was inversely related to their birth weight (P < 0.0001) and directly related to their current weight. Glycated haemoglobin level was higher in children with thicker triceps skinfolds (P < 0.001) and who had been shorter at birth (P = 0.003). Serum cholesterol concentration was inversely related to current height (P = 0.001) and to length at birth (P = 0.09) and was directly related to triceps skinfold thickness and higher socioeconomic status (P < 0.001).
Blood pressure in childhood was inversely related to birth weight and directly to current weight. Glycaemic control and serum cholesterol were related to short length at birth, height deficit in childhood, and childhood obesity.
确定学童的血压、糖化血红蛋白水平、胆固醇浓度与他们的人体测量数据、社会经济地位及出生时测量数据之间的关系。
回顾性队列研究。
牙买加金斯敦西印度群岛大学医院附近的27所学校。
招募了2337名在大学医院出生的6至16岁儿童，并找回了他们的出生记录：1610名儿童有合适的记录，659名儿童的记录包含出生身长，其中610名处于青春期前。
血压、糖化血红蛋白水平、血清胆固醇浓度、出生时的人体测量数据、当前人体测量数据及社会经济地位。
多元回归分析显示，儿童的收缩压与出生体重呈负相关（P < 0.0001），与当前体重呈正相关。三头肌皮褶较厚的儿童（P < 0.001）及出生时较短的儿童（P = 0.003）糖化血红蛋白水平较高。血清胆固醇浓度与当前身高呈负相关（P = 0.001），与出生身长呈负相关（P = 0.09），与三头肌皮褶厚度及较高的社会经济地位呈正相关（P < 0.001）。
儿童期血压与出生体重呈负相关，与当前体重呈正相关。血糖控制及血清胆固醇与出生时身长较短、儿童期身高不足及儿童肥胖有关。
