Calev A, Gaudino E A, Squires N K, Zervas I M, Fink M
Department of Psychiatry and Behavioral Science, State University of New York at Stony Brook 11794-8101, USA.
Br J Clin Psychol. 1995 Nov;34(4):505-15. doi: 10.1111/j.2044-8260.1995.tb01485.x.
The literature on the effects of electroconvulsive therapy (ECT) on non-memory cognitive functions is reviewed. It is concluded that with early methods of ECT administration (sine wave, high dose), these effects are larger than those of depression. They are less pronounced, and usually do not exceed the effects of depression, when modern methods of ECT administration (brief pulse, moderate or low dose) are used. Following ECT, these functions progressively improve. At one week to seven months after ECT, performance is better than before ECT, probably because of the alleviation of both the effects of depression and of ECT. The time course to full recovery of the non-memory effects resembles that of the recovery of amnesic effects, although the latter are more pronounced. With bilateral ECT, as with right unilateral ECT, there is evidence that right hemisphere effects are more pronounced. The results of this review argue that clinicians should take the non-memory cognitive effects of ECT into account, and patients should be informed of their existence before they sign consent for ECT.
本文回顾了关于电休克疗法（ECT）对非记忆认知功能影响的文献。得出的结论是，采用早期的ECT给药方法（正弦波、高剂量）时，这些影响比抑郁症本身的影响更大。而使用现代的ECT给药方法（短脉冲、中等或低剂量）时，这些影响则不那么明显，通常也不会超过抑郁症本身的影响。ECT治疗后，这些功能会逐渐改善。在ECT治疗后的一周至七个月内，患者的表现比ECT治疗前更好，这可能是因为抑郁症和ECT的影响都得到了缓解。非记忆功能完全恢复的时间进程与遗忘症恢复的时间进程相似，尽管后者更为明显。有证据表明，双侧ECT和右侧单侧ECT一样，右侧半球的影响更为明显。本文的研究结果表明，临床医生应考虑ECT对非记忆认知的影响，并且在患者签署ECT同意书之前，应告知他们这些影响的存在。
