el-Rab M O, al-Sheikh O A
Immunology Division, King Khalid University Hospital, College of Medicine, Riyadh, Saudi Arabia.
Contact Dermatitis. 1995 Nov;33(5):310-4. doi: 10.1111/j.1600-0536.1995.tb02044.x.
Due to the lack of a regional patch test series in our geographical area, the suitability of the European standard series was evaluated by patch testing dermatitis patients in Riyadh, Saudi Arabia. Of 240 consecutive patients with various forms of dermatitis, 136 (57%) showed 1 or more positive patch tests, women, 74 (54%), slightly outnumbering men, 62 (46%). Positive reactions were found to 21 of the 22 items in the test series. Sensitization was most common to nickel sulfate (51 = 37.5%), potassium dichromate (48 = 35%) and cobalt chloride (43 = 32%) The frequency of sensitization to nickel was higher in women (41 = 30%) while that to dichromate was higher in men (39 = 29%). Less reactions were found to fragrance mix (21 = 15%), formaldehyde (15 = 11%) and neomycin sulfate (15 = 11%). Sensitization to other allergens ranged between 10 and 1%. Less than 1% of patients (0.7%) reacted to benzocaine and none to primin. The frequency of occurrence of multiple sensitivities is also presented. We conclude that the European standard series is suitable for patch testing dermatitis patients in our region, with the exception of benzocaine and primin. The addition of 3 allergens that could be of local relevance is discussed.
由于我们所在地理区域缺乏区域性斑贴试验系列，因此通过对沙特阿拉伯利雅得的皮炎患者进行斑贴试验，评估了欧洲标准系列的适用性。在连续的240例各种形式的皮炎患者中，136例（57%）的斑贴试验显示1项或更多项阳性，女性74例（54%）略多于男性62例（46%）。在试验系列的22项中，有21项出现了阳性反应。最常见的致敏原是硫酸镍（51例 = 37.5%）、重铬酸钾（48例 = 35%）和氯化钴（43例 = 32%）。女性对镍的致敏频率较高（41例 = 30%），而男性对重铬酸盐的致敏频率较高（39例 = 29%）。对香料混合物（21例 = 15%）、甲醛（15例 = 11%）和硫酸新霉素（15例 = 11%）的反应较少。对其他过敏原的致敏率在10%至1%之间。不到1%的患者（0.7%）对苯佐卡因有反应，对樱草灵无反应。还列出了多重致敏的发生频率。我们得出结论，除苯佐卡因和樱草灵外，欧洲标准系列适用于我们地区的皮炎患者斑贴试验。讨论了添加3种可能具有局部相关性的过敏原。
