Sharma V K, Chakrabarti A
Department of Dermatology, Venereology & Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Contact Dermatitis. 1998 Mar;38(3):127-31. doi: 10.1111/j.1600-0536.1998.tb05677.x.
200 patients (122 male, 78 female) with suspected allergic contact dermatitis were patch tested with the European standard series (ESS) and the results compared with other Asian centres. 131 (65.5%) patients showed 1 or more patch test positives to the ESS. Patch tests were positive to all allergens except primin. Potassium dichromate was the most common allergen (20.5%) followed by nickel sulfate (16.5%), SQL mix (14%), PPD (11.5%), cobalt (8%), fragrance mix (7.5%), formaldehyde (6.5%), colophony (5.5%), neomycin sulfate and mercapto mix (5% each). In women, nickel sulfate was the commonest allergen (30.8%) followed by SQL mix (16.7%) and potassium dichromate (15.4%). In men, potassium dichromate was the commonest sensitizer (23.8%) followed by SQL mix and PPD (12.3% each). Our results are at variance with other centres in Asia. SQL mix was able to detect less than 1/2 (42.2%) of patients allergic to ethanolic dilutions of ether extracts of parthenium. We conclude that the European standard series, with exclusion of primin, is suitable for detection of allergic contact dermatitis in India. However, SQL mix is not a adequate screen for parthenium sensitivity and patch testing with extracts of the plant should be continued, wherever indicated.
200例疑似过敏性接触性皮炎患者（男性122例，女性78例）接受了欧洲标准系列（ESS）斑贴试验，并将结果与其他亚洲中心进行了比较。131例（65.5%）患者对ESS斑贴试验显示1种或更多阳性反应。除了致敏原外，对所有变应原的斑贴试验均呈阳性。重铬酸钾是最常见的变应原（20.5%），其次是硫酸镍（16.5%）、SQL混合液（14%）、对苯二胺（11.5%）、钴（8%）、香料混合液（7.5%）、甲醛（6.5%）、松香（5.5%）、硫酸新霉素和巯基混合液（各5%）。在女性中，硫酸镍是最常见的变应原（30.8%），其次是SQL混合液（16.7%）和重铬酸钾（15.4%）。在男性中，重铬酸钾是最常见的致敏原（23.8%），其次是SQL混合液和对苯二胺（各12.3%）。我们的结果与亚洲其他中心不同。SQL混合液只能检测到不到1/2（42.2%）对银胶菊乙醇提取物过敏的患者。我们得出结论，排除致敏原的欧洲标准系列适用于印度过敏性接触性皮炎的检测。然而，SQL混合液对银胶菊敏感性的筛查并不充分，无论何处有指征，都应继续用该植物提取物进行斑贴试验。
