Naylor S L, Moore S, Garcia D, Xiang X, Xin X, Mohrer M, Reus B, Linn R, Stanton V, O'Connell P, Leach R J
Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio 78284-7762, USA.
Cytogenet Cell Genet. 1996;72(1):90-4. doi: 10.1159/000134170.
The initial step of mapping STSs to chromosome 3 has been by mapping to a reference panel of 21 somatic cell hybrids containing fragments of chromosome 3. In this study we map 638 STSs to 23 bins on chromosome 3. The bin information greatly facilitates further mapping by radiation hybrids and YAC clones.
将序列标签位点(STSs)定位到3号染色体上的第一步是将其定位到一个由21个包含3号染色体片段的体细胞杂种组成的参考面板上。在本研究中,我们将638个STSs定位到3号染色体上的23个区间。这些区间信息极大地促进了通过辐射杂种和酵母人工染色体(YAC)克隆进行的进一步定位。