Soyka M
Psychiatrische Klinik und Poliklinik, Universität München, Munich, Germany.
Drug Alcohol Depend. 1995 Sep;39 Suppl 1:S9-13. doi: 10.1016/0376-8716(95)01168-x.
Although past alcoholism treatment in Germany has primarily focused on psychotherapy, new advances in pharmacotherapy are expanding therapeutic options. Recent biomedical studies have produced new theories about how alcohol affects neurotransmitters in the brain. These studies have led to new pharmacologic strategies for the treatment of alcoholism using dopamine agonists and antagonists, serotoninergic agents, glutamate antagonists, and opiate antagonists. While preliminary studies of these agents offer encouraging results, it remains to be demonstrated which agent(s) will provide effective pharmacotherapy for this disease.
尽管德国过去的酒精成瘾治疗主要集中在心理治疗上，但药物治疗的新进展正在扩大治疗选择。最近的生物医学研究产生了关于酒精如何影响大脑神经递质的新理论。这些研究导致了使用多巴胺激动剂和拮抗剂、血清素能药物、谷氨酸拮抗剂和阿片拮抗剂治疗酒精成瘾的新药物策略。虽然对这些药物的初步研究提供了令人鼓舞的结果，但哪种药物将为这种疾病提供有效的药物治疗仍有待证明。
