Pakrashi A, Chatterjee S
Indian Institute of Chemical Biology, Calcutta, India.
Int J Androl. 1995 Oct;18(5):232-6.
The function of accessory sex glands in 29 tobacco smokers, 25 tobacco chewers and 30 non-users of tobacco was investigated by determining the ejaculate contents of various glandular markers: N-acetyl amino sugar and total phosphate (seminal vesicles) zinc and acid phosphatase (prostate gland), and alpha-1,4-glucosidase (epididymis). Both vesicular and prostatic parameters were reduced significantly in smokers compared with non-users of tobacco, whereas these parameters were unchanged in tobacco chewers. This difference may be due either to the difference in constitution of xenobiotics emitted as a result of burning tobacco, or to differences in the pharmacokinetics of the two forms of tobacco consumption. The activity of alpha-1,4-glucosidase was significantly lowered in both types of tobacco users. It is concluded that use of tobacco, especially by smoking, impairs the secretory function of accessory sex glands in man.
通过测定各种腺体标志物的射精含量，对29名吸烟者、25名嚼烟者和30名不使用烟草者的附属性腺功能进行了研究：N - 乙酰氨基糖和总磷酸盐（精囊）、锌和酸性磷酸酶（前列腺）以及α-1,4-葡萄糖苷酶（附睾）。与不使用烟草者相比，吸烟者的精囊和前列腺参数均显著降低，而嚼烟者的这些参数没有变化。这种差异可能是由于燃烧烟草释放的外源性物质组成不同，或者是由于两种烟草消费形式的药代动力学差异。两种类型的烟草使用者中α-1,4-葡萄糖苷酶的活性均显著降低。得出的结论是，使用烟草，尤其是吸烟，会损害男性附属性腺的分泌功能。
