Schwarz T F, Jäger G
Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwing-Maximilians-Universität, München.
Hautarzt. 1995 Dec;46(12):831-5. doi: 10.1007/s001050050348.
Human parvovirus B19 causes erythema infectiosum (fifth disease) and aplastic crisis. In pregnancy, B19 may be transmitted on to the fetus resulting in hydrops fetalis. B19 is sometimes associated with thrombocytopenia and vasculitis. In immunocompromised patients, B19 may persist causing chronic infection. Several methods for detecting B19 virus or specific antibodies are now available. B19 infection does not usually require therapy. Efficacy of immunoglobulins in chronic B19 infection has been demonstrated.
人细小病毒B19可引起传染性红斑（第五病）和再生障碍危象。在孕期，B19可传播给胎儿，导致胎儿水肿。B19有时与血小板减少症和血管炎相关。在免疫功能低下的患者中，B19可能持续存在，引起慢性感染。目前有几种检测B19病毒或特异性抗体的方法。B19感染通常无需治疗。免疫球蛋白对慢性B19感染的疗效已得到证实。
