Caillaud C, Serre-Cousiné O, Anselme F, Capdevilla X, Préfaut C
Laboratoire de Physiologie des Interactions, Hopital Arnaud de Villeneuve, Montpellier, France.
J Appl Physiol (1985). 1995 Oct;79(4):1226-32. doi: 10.1152/jappl.1995.79.4.1226.
We investigated the computerized tomographies (CTs) of the thorax and the pulmonary diffusing capacity for CO (DLCO) in eight male athletes before and after a triathlon. DLCO and alveolar volume (VA) were simultaneously measured during 9 s of breath holding. The transfer coefficient (KCO = DLCO/VA) was then calculated. CT scanning was performed during breath holding with the subjects in the supine position. Scanner analysis was done by 1) counting the linear and polygonal opacities (index of interstitial fluid accumulation) and 2) calculating the physical mean lung density and the mean slice mass. Results showed a significant reduction in DLCO (44.9 +/- 2.3 vs. 42.9 +/- 1.7 ml.min-1.mmHg-1; P < 0.05) and KCO (6.0 +/- 0.3 vs. 5.6 +/- 0.3 ml.min-1.mmHg-1.l of VA-1; P < 0.05) after the triathlon and an increase in mean lung density (0.21 +/- 0.009 vs. 0.25 +/- 0.01 g/cm3; P < 0.0001). The number of polygonal and linear opacities increased after the race (P < 0.001). This study confirmed that DLCO and KCO decrease in elite athletes after a long-distance race and showed a concomitant increase in CT lung density and in the number of opacities.
我们对八名男性运动员在铁人三项比赛前后的胸部计算机断层扫描（CT）和一氧化碳肺弥散量（DLCO）进行了研究。在屏气9秒期间同时测量DLCO和肺泡容积（VA），然后计算转移系数（KCO = DLCO/VA）。受试者仰卧位屏气时进行CT扫描。扫描分析通过以下方式进行：1）计算线性和多边形混浊（间质液积聚指数）；2）计算肺物理平均密度和平均切片质量。结果显示，铁人三项比赛后，DLCO（44.9±2.3 vs. 42.9±1.7 ml·min⁻¹·mmHg⁻¹；P < 0.05）和KCO（6.0±0.3 vs. 5.6±0.3 ml·min⁻¹·mmHg⁻¹·l of VA⁻¹；P < 0.05）显著降低，肺平均密度增加（0.21±0.009 vs. 0.25±0.01 g/cm³；P < 0.0001）。比赛后多边形和线性混浊数量增加（P < 0.001）。本研究证实，精英运动员在长跑后DLCO和KCO降低，同时CT肺密度和混浊数量增加。
