Stalf T, Sánchez R, Köhn F M, Schalles U, Kleinstein J, Hinz V, Tielsch J, Khanaga O, Turley H, Gips H
Department of Dermatology and Andrology, Justus Liebig University, Gìessen, Germany.
Hum Reprod. 1995 Aug;10(8):2112-4. doi: 10.1093/oxfordjournals.humrep.a136244.
Tail stump syndrome, which may be associated with primary ciliary dyskinesia, is also associated with morphological defects of the flagellum resulting in severe asthenozoospermia. Until recently, these morphological anomalies caused definite male infertility. Today, however, new methods such as micromanipulation techniques provide a rational therapy for this patient group. A pregnancy followed by living offspring was achieved following the intracytoplasmic injection of immotile spermatozoa from a patient with tail stump syndrome.
尾残端综合征可能与原发性纤毛运动障碍相关，也与鞭毛形态缺陷有关，可导致严重的弱精子症。直到最近，这些形态异常仍会导致明确的男性不育。然而如今，诸如显微操作技术等新方法为这一患者群体提供了合理的治疗方案。通过对一名患有尾残端综合征患者的不动精子进行胞浆内注射后，实现了妊娠并诞下存活后代。
