Biljan M M, Hewitt J, Kingsland C R, Taylor C T
Reproductive Medicine Unit, Liverpool Women's Hospital, UK.
Hum Reprod. 1995 Aug;10(8):2169-70. doi: 10.1093/oxfordjournals.humrep.a136255.
A study of a 25 year old woman with a previous history of tubal damage, ectopic pregnancy and unsuccessful tubal surgery is reported. Following in-vitro fertilization (IVF) treatment, four viable fetuses were revealed by ultrasound scan at 10 weeks gestation. Two shared the same gestational sac, thus establishing a trizygotic quadruplet pregnancy. The implications of monozygotic twinning in humans are discussed. It is concluded that embryo splitting and its consequences should be seriously considered when multiple embryo transfer in young patients is contemplated.
报道了一名25岁女性的病例，该女性既往有输卵管损伤、异位妊娠史且输卵管手术失败。体外受精（IVF）治疗后，妊娠10周时超声检查发现有4个存活胎儿。其中两个共享同一个妊娠囊，从而确诊为三受精卵四胎妊娠。文中讨论了人类单卵双胎的影响。得出的结论是，在考虑对年轻患者进行多胚胎移植时，应认真考虑胚胎分裂及其后果。
