Simultaneous determination of anticonvulsant drugs by gas-liquid chromatography.
作者信息
Hill R E, Latham A N
出版信息
J Chromatogr. 1977 Jan 21;131:341-6. doi: 10.1016/s0021-9673(00)80950-4.
PMID:856856
Abstract
A quantitative gas-liquid chromatographic method for the determination of blood levels of ethosuximide, phenobarbitone, primidone and diphenylhydantoin is described. All four compounds are determined using 1 ml of serum. A simple, direct extraction technique is employed. Ethosuximide is analysed without derivatization. Subsequent flash alkylation with trimethylanilinium hydroxide allows the simultaneous determination of phenobarbitone, primidone, and diphenylhydantoin.
摘要
相似文献
1
Simultaneous determination of anticonvulsant drugs by gas-liquid chromatography.
J Chromatogr. 1977 Jan 21;131:341-6. doi: 10.1016/s0021-9673(00)80950-4.
2
Simultaneous quantitative gas-chromatographic analysis of ethosuximide, phenobarbitone, primidone and diphenylhydantoin.乙琥胺、苯巴比妥、扑米酮和苯妥英的同步定量气相色谱分析。
Br J Clin Pharmacol. 1976 Feb;3(1):145-50. doi: 10.1111/j.1365-2125.1976.tb00581.x.
3
4
Evaluation of a rapid gas-chromatographic method for the simultaneous quantitative determination of ethosuximide, phenyletheylmalonediamide, carbamazepine, phenobarbital, primidone and diphenylhydantoin in human serum.
Clin Chim Acta. 1977 Jun 15;77(3):307-16. doi: 10.1016/0009-8981(77)90234-0.
5
Accuracy of serum anticonvulsant measurements. A comparison of enzyme multiplied immunoassay technique and gas-liquid chromatography.血清抗惊厥药测定的准确性。酶放大免疫分析技术与气液色谱法的比较。
Ann Clin Biochem. 1979 Jul;16(4):205-8. doi: 10.1177/000456327901600148.
6
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.对同一血清样本中的苯妥英、苯巴比妥、扑米酮、苯乙基丙二酰胺、卡马西平、三甲双酮、二甲双酮、乙琥胺和丙戊酸盐进行连续气相色谱测定。
Epilepsia. 1978 Oct;19(5):463-73. doi: 10.1111/j.1528-1157.1978.tb05173.x.
7
Simultaneous high-pressure liquid-chromatographic determination of some anticonvulsants in serum.血清中某些抗惊厥药的高压液相色谱同步测定法
Clin Chem. 1976 Jan;22(1):25-31.
8
Improved method for the simultaneous determination of phenobarbital, primidone and diphenylhydantoin in patient's serum by gas-liquid chromatography.
J Chromatogr. 1975 Apr 9;107(1):61-6. doi: 10.1016/s0021-9673(00)82747-8.
9
Rapid determination of anticonvulsant drugs by isothermal gas-liquid chromatography.
J Chromatogr. 1981 Mar 13;222(3):486-90. doi: 10.1016/s0378-4347(00)84152-3.
10
The simultaneous determination of multiple anticonvulsant drug levels by gas-liquid chromatography. Method and clinical application.
Neurology. 1972 May;22(5):540-50. doi: 10.1212/wnl.22.5.540.
Zotero 插件