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不同尺寸起搏器导线植入后阈值的比较研究(作者译)

[Comparative studies of thresholds after implantation of pacemaker leads of different size (author's transl)].

作者信息

Kleinert M, Irnich W, Beer P

出版信息

Z Kardiol. 1977 Apr;66(4):191-7.

PMID:857458
Abstract

Within the first 14 days after implantation, thresholds were measured at three transvenous pacemaker electrodes with different surface areas. It should be verified, 1. to what extent a correlation existed between maximal threshold increase and electrode surface, 2. how electrode impedance and 3. how the amplitudes of the R-wave voltages developed. The results were: At initial implantation, thresholds were all the lower the smaller the electrode-surface area was. On overage, 9-10 days after implantation the highest thresholds were reached. Thereby, in small surface area electrodes the threshold-increase factor was greater than in larger ones. In all cases the current threshold increase exceeded that one for voltage thresholds. 14 days later, thresholds had dropped again compared to the maximum. And this decrease was depending on the electrode-surface area also. The electrode impedance decreased after implantation to rise later on once more to 80-88% of the original value. The magnitude of the detected R-wave was independent on electrode-surface area. Indeed, using small surface electrodes, signal reductions up to 50% could be found. But 14 days later they reached again 80-95% of the initial amplitude. The key finding there is that when applying small surface-area electrodes and presuming suitable initial thresholds it seems to be possible to connect low-output pacemakers (output 5,4 V and impluse duration 0.25 ms or 4 V at 0.5 ms) to those electrodes. By this reduction of the safety margin, a considerable increase in pacemaker lifetime could be achieved.

摘要

在植入后的前14天内,对三个具有不同表面积的经静脉起搏器电极进行了阈值测量。需要验证:1. 最大阈值增加与电极表面积之间存在何种程度的相关性;2. 电极阻抗情况;3. R波电压的幅度如何变化。结果如下:在初次植入时,电极表面积越小,阈值越低。平均而言,植入后9至10天达到最高阈值。因此,小表面积电极的阈值增加因子大于大表面积电极。在所有情况下,电流阈值的增加超过了电压阈值。14天后,与最大值相比,阈值再次下降。而且这种下降也取决于电极表面积。植入后电极阻抗下降,随后又再次上升至原始值的80 - 88%。检测到的R波幅度与电极表面积无关。实际上,使用小表面积电极时,信号减少可达50%。但14天后,它们再次达到初始幅度的80 - 95%。关键发现是,当使用小表面积电极并假定初始阈值合适时,似乎可以将低输出起搏器(输出5.4V,脉冲持续时间0.25ms或0.5ms时为4V)连接到这些电极上。通过这种安全裕度的降低,可以显著延长起搏器的使用寿命。

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