Nechaeva I P, Bunin K V, Kravtsov E G, Flerova N K, Firsanov V I
Zh Mikrobiol Epidemiol Immunobiol. 1977 Mar(3):88-91.
The authors studied the quantitative content of nonspecific immunoglobulins and antibodies of the IgG-, IgA-, and IgM-classes to the O-antigen of the cholera vibrio. There proved to be no marked dynamics of the quantitative immunoglobulins indices of various classes established at periods from the 3rd and the 18th day from the beginning of the disease in persons who sustained cholera. In persons who sustained cholera in the nonendemic focus of the disease serum antibodies were represented chiefly by the IgM-antibodies. The formation of IgA-antibodies in the persons examined differed from the regularities detected for the IgG- and IgM-classes and were characterized by rapidity and short duration. No correlation was found between the immunoglobulin levels of various classes and the serum antibody levels in case of cholera affection.
作者研究了非特异性免疫球蛋白以及IgG、IgA和IgM类抗体针对霍乱弧菌O抗原的定量含量。结果表明，在霍乱患者中，从疾病开始后的第3天到第18天期间所确定的各类免疫球蛋白指标并无明显动态变化。在疾病非流行区患霍乱的人群中，血清抗体主要以IgM抗体为主。受检者体内IgA抗体的形成与IgG和IgM类抗体的形成规律不同，其特点是快速且持续时间短。在霍乱感染情况下，未发现各类免疫球蛋白水平与血清抗体水平之间存在相关性。
