Prabhu M S, Platel K, Saraswathi G, Srinivasan K
Department of Studies in Food Sciences and Nutrition, University of Mysore, Manasagangotri.
Indian J Exp Biol. 1995 Oct;33(10):752-6.
The influence of two varieties of betel leaf (Piper betle Linn.) namely, the pungent Mysore and non-pungent Ambadi, was examined on digestive enzymes of pancreas and intestinal mucosa and on bile secretion in experimental rats. The betel leaves were administered orally at two doses which were either comparable to human consumption level or 5 times this. The results indicated that while these betel leaves do not influence bile secretion and composition, they have a significant stimulatory influence on pancreatic lipase activity. Besides, the Ambadi variety of betel leaf has a positive stimulatory influence on intestinal digestive enzymes, especially lipase, amylase and disaccharidases. A slight lowering in the activity of these intestinal enzymes was seen when Mysore variety of betel leaf was administered, and this variety also had a negative effect on pancreatic amylase. Further, both the betel leaf varieties have shown decreasing influence on pancreatic trypsin and chymotrypsin activities.
研究了两种槟榔叶（蒌叶），即辛辣的迈索尔槟榔叶和不辣的安巴迪槟榔叶，对实验大鼠胰腺和肠黏膜消化酶以及胆汁分泌的影响。以与人类食用水平相当或5倍于此的两种剂量口服给予槟榔叶。结果表明，这些槟榔叶虽然不影响胆汁分泌和成分，但对胰腺脂肪酶活性有显著的刺激作用。此外，安巴迪品种的槟榔叶对肠道消化酶，尤其是脂肪酶、淀粉酶和双糖酶有积极的刺激作用。当给予迈索尔品种的槟榔叶时，这些肠道酶的活性略有降低，并且该品种对胰腺淀粉酶也有负面影响。此外，两种槟榔叶品种对胰腺胰蛋白酶和糜蛋白酶活性均显示出降低作用。
