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智利北部前哥伦布时期的结核病:分子与骨骼证据

Pre-Columbian tuberculosis in northern Chile: molecular and skeletal evidence.

作者信息

Arriaza B T, Salo W, Aufderheide A C, Holcomb T A

机构信息

Department of Anthropology, University of Nevada, Las Vegas 89154-5012, USA.

出版信息

Am J Phys Anthropol. 1995 Sep;98(1):37-45. doi: 10.1002/ajpa.1330980104.

DOI:10.1002/ajpa.1330980104
PMID:8579189
Abstract

Analysis of 483 skeletons from Arica (Chile) and review of mummy dissection records demonstrates an overall 1% prevalence rate for tuberculosis between 2000 B.C. and A.D. 1500. Tuberculosis cases cluster in the period A.D. 500-1000 which correlates with fully agropastoral societies. Considering only these agropastoral societies, about 2% of their members show tuberculosis lesions. A segment of DNA unique to Mycobacterium tuberculosis was identified in an extract from the vertebral lesion of a 12-year-old girl with Pott's disease from about A.D. 1000, establishing the pre-Columbian presence of tuberculosis with the most specific evidence currently available.

摘要

对来自智利阿里卡的483具骨骼的分析以及对木乃伊解剖记录的回顾表明,在公元前2000年至公元1500年期间,结核病的总体患病率为1%。结核病病例集中在公元500年至1000年期间,这与完全的农牧社会相关。仅考虑这些农牧社会,约2%的成员有结核病病变。在一名来自公元1000年左右患有波特氏病的12岁女孩的脊椎病变提取物中,鉴定出了结核分枝杆菌特有的一段DNA,这是目前可用的最具体证据,证实了结核病在哥伦布发现美洲大陆之前就已存在。

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