Bujía J, Kastenbauer E, Wilmes E, Gürtler L
Klinik und Poliklinik für Hals-Nasen- und Ohrenkranke.
Laryngorhinootologie. 1995 Dec;74(12):761-4. doi: 10.1055/s-2007-997840.
Because of the limited availability of autologous tissue, stored allograft is commonly used. Before grafting, bank tissue is subjected to chemical preservation procedures. This procedure is important to diminish antigenicity and to inactivate possible inherent viruses. The aim of this study was to determine the influence of different chemical preservation procedures like Cialit, Merthiolate, and formaldehyde on the presence of HIV DNA.
HIV-infected tissues were obtained from eight HIV-positive patients and examined using the polymerase chain reaction (PCR).
After chemical treatment, we could observe the presence of HIV DNA in all examined tissues.
The findings indicate the importance of the mandatory serological screening and selection in donor patients.
由于自体组织供应有限，通常使用储存的同种异体移植物。在移植前，库存组织要经过化学保存程序。此程序对于降低抗原性和灭活可能存在的固有病毒很重要。本研究的目的是确定不同化学保存程序（如西阿利特、硫柳汞和甲醛）对HIV DNA存在情况的影响。
从八名HIV阳性患者获取感染HIV的组织，并使用聚合酶链反应（PCR）进行检测。
化学处理后，我们在所有检测的组织中都观察到了HIV DNA的存在。
研究结果表明对供体患者进行强制性血清学筛查和选择的重要性。
