一种核苷酸序列模型。
A model for nucleotide sequences.
作者信息
de Souza A M, Anteneodo C
机构信息
Centro Brasileiro de Pesquisas Fisicas, Rio de Janeiro, Brazil.
出版信息
Biophys J. 1995 Nov;69(5):1708-11. doi: 10.1016/S0006-3495(95)80040-8.
Abstract
We propose a model for generating "artificial" nucleotide sequences and, by the method of mapping those sequences onto a "DNA-walk," we analyze the presence of correlation between nucleotides. Artificial sequences are constructed considering, basically, interactions between first neighbors and between more distant units. We show that long-range correlations may be favored by the occurrence of intrastrand interactions, which give a nonlinear characteristic to the sequence.
摘要
我们提出了一种用于生成“人工”核苷酸序列的模型，并通过将这些序列映射到“DNA 行走”的方法，分析核苷酸之间相关性的存在情况。基本上，在构建人工序列时考虑了相邻核苷酸之间以及更远距离单元之间的相互作用。我们表明，链内相互作用的出现可能有利于长程相关性，这赋予了序列非线性特征。
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