Evans A R, Hancock B W, Brown M J, Richmond J
Br Med J. 1977 Apr 23;1(6068):1056-7. doi: 10.1136/bmj.1.6068.1056.
Nine cases of Hodgkin's disease and one of acute lymphoblastic leukaemia occurred in 1972-5 in an area of less than 1 km. Clinical, social, and drug histories provided no relevant information, and definite patient-to-patient contacts before the onset of disease were not established. There was a higher incidence of malignant neoplasms in first-degree relatives of the patients than in those of a small control group living in the same area. There was no apparent reason for this cluster of cases, but geographical, climatic, and entomological studies are being carried out.
1972年至1975年间,在面积不足1平方公里的区域内出现了9例霍奇金病和1例急性淋巴细胞白血病。临床、社会及用药史均未提供相关信息,且未确定疾病发作前患者之间的确切接触情况。患者一级亲属中恶性肿瘤的发病率高于居住在同一地区的小对照组亲属。目前尚不清楚这组病例出现的明显原因,但正在开展地理、气候和昆虫学研究。