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通过体重预测用于活体肝移植的供肝叶重量。

Predicting the donor liver lobe weight from body weight for split-liver transplantation.

作者信息

Chaib E, Morales M M, Bordalo M B, Antonio L G, Feijo L F, Ishida R Y, Lima Júnior J, Nunes P A

机构信息

Departamento de Gastroenterologia, Faculdade de Medicina, Universidade de São Paulo, Brasil.

出版信息

Braz J Med Biol Res. 1995 Jul;28(7):759-60.

PMID:8580866
Abstract

It is possible to obtain two good-quality hepatic transplants from a single cadaveric liver by separation of the right and left lobes of the liver. We attempted to define a relationship based only on donor body weight for predicting donor total liver weight as well as donor right (segments V-VIII) and left (segments II-IV) hepatic lobe weight. Segment I (caudate lobe) is resected and thus lost in this procedure. The study was performed on 60 human cadaveric livers. We correlated cadaveric body weight (mean +/- SD), 72.43 +/- 9.54 kg, with total liver weight, 1.54 +/- 0.36 kg, and right and left lobe weight, 0.88 +/- 0.23 kg and 0.65 +/- 0.17 kg, respectively, with total liver weight. A formula was obtained by linear regression which provided the following relationships: total liver weight (g) = [245.57 + 17.92 x (body weight, kg)]; right lobe weight (g) = [67.58 + 0.52 x (total liver weight, g)]; left lobe weight (g) = [-63.38 + 0.47 x (total liver weight, g)]. The selection of the recipient on the liver transplant waiting list can be made on the basis of these relationships.

摘要

通过分离肝脏的左右叶,从单个尸体肝脏中获取两个高质量的肝移植供体是可行的。我们试图仅基于供体体重来定义一种关系,以预测供体全肝重量以及供体右肝叶(第V - VIII段)和左肝叶(第II - IV段)的重量。在这个过程中,第I段(尾状叶)被切除并因此丢失。该研究对60个人类尸体肝脏进行。我们将尸体体重(均值±标准差),即72.43±9.54千克,与全肝重量1.54±0.36千克以及右叶和左叶重量(分别为0.88±0.23千克和0.65±0.17千克)与全肝重量进行关联。通过线性回归得到一个公式,该公式给出了以下关系:全肝重量(克)= [245.57 + 17.92×(体重,千克)];右叶重量(克)= [67.58 + 0.52×(全肝重量,克)];左叶重量(克)= [-63.38 + 0.47×(全肝重量,克)]。肝移植等待名单上受体的选择可以基于这些关系来进行。

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