Andersen A E, Woodward P J, LaFrance N
Department of Psychiatry, UIHC, Iowa City 52242-1057, USA.
Int J Eat Disord. 1995 Dec;18(4):335-42. doi: 10.1002/1098-108x(199512)18:4<335::aid-eat2260180406>3.0.co;2-t.
We tested nine hypotheses among eating disorder subgroups and a control group on spinal bone density and investigated the relationship of their spinal bone density with a critical fracture threshold and five clinical variables--age of onset, years ill, percentage of ideal body weight (IBW), months of amenorrhea, and hours per week of exercise.
Dual photon absorptiometry measured spinal bone density.
Anorectic patients had significantly less spinal bone mass than bulimic patients with no history of anorexia nervosa or control patients. Eating disordered patients with past or present anorexia nervosa had significantly more spinal bone density values below a critical fracture threshold. Duration of amenorrhea and exercise significantly predicted spinal bone density.
Anorectic women were unlikely to reach their peak bone density, thus possibly developing osteoporosis later in life, and were likely to be at risk for nontraumatic spinal fractures. Predicting spinal bone density of anorectic women could be done by knowing their duration of amenorrhea and exercise.
我们在饮食失调亚组和一个对照组中检验了九个关于脊柱骨密度的假设，并研究了他们的脊柱骨密度与临界骨折阈值以及五个临床变量（发病年龄、患病年限、理想体重百分比、闭经月数和每周运动小时数）之间的关系。
采用双能光子吸收法测量脊柱骨密度。
神经性厌食症患者的脊柱骨量明显低于无神经性厌食症病史的贪食症患者或对照组患者。有过去或现在神经性厌食症病史的饮食失调患者，其脊柱骨密度值低于临界骨折阈值的情况明显更多。闭经持续时间和运动对脊柱骨密度有显著预测作用。
神经性厌食症女性不太可能达到其峰值骨密度，因此可能在晚年患骨质疏松症，并且有非创伤性脊柱骨折的风险。通过了解神经性厌食症女性的闭经持续时间和运动情况，可以预测她们的脊柱骨密度。
