To W W, Leung W C
Department of Obstetrics and Gynecology, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.
Int J Gynaecol Obstet. 1995 Oct;51(1):25-31. doi: 10.1016/0020-7292(95)80004-v.
To assess the relationship between previous cesarean section and subsequent development of placenta previa and placenta previa with accreta.
The records of all patients delivered with the diagnosis of placenta previa during the 10-year period from 1984 to 1993 were reviewed.
From a total of 50,485 deliveries, 421 (0.83%) had placenta previa, 43 (10.2%) of whom had a history of previous cesarean section. The incidence of placenta previa was significantly increased in those with a previous cesarean section (1.31%) compared with those with an unscarred uterus (0.75%) (R.R. 1.64). This risk increased as the number of previous cesarean sections increased (R.R. 1.53 for one previous section, 2.63 for two or more). The incidence of an anterior placenta previa and placenta accreta was significantly increased in those with previous cesarean scars. The incidence of placenta accreta was 1.18% among patients with placenta previa, 80% being in patients with previous cesarean section. The relative risk for placenta accreta in patients with placenta previa was 35 times higher in those with a previous cesarean section than in those with an unscarred uterus.
The association of previous cesarean section with placenta previa and placenta previa accreta is confirmed. Patients with an antepartum diagnosis of placenta previa who have had a previous cesarean section should be considered at high risk for developing placenta accreta.
评估既往剖宫产与前置胎盘及植入性前置胎盘后续发生之间的关系。
回顾了1984年至1993年这10年间所有诊断为前置胎盘的分娩患者的记录。
在总共50485例分娩中,421例(0.83%)为前置胎盘,其中43例(10.2%)有既往剖宫产史。既往有剖宫产史者前置胎盘的发生率(1.31%)显著高于子宫无瘢痕者(0.75%)(相对危险度1.64)。随着既往剖宫产次数的增加,这种风险也增加(既往剖宫产一次的相对危险度为1.53,两次或更多次为2.63)。既往有剖宫产瘢痕者前置胎盘及植入性胎盘的发生率显著增加。前置胎盘患者中植入性胎盘的发生率为1.18%,其中80%为既往有剖宫产史的患者。前置胎盘患者中,既往有剖宫产史者发生植入性胎盘的相对危险度比子宫无瘢痕者高35倍。
证实了既往剖宫产与前置胎盘及植入性前置胎盘之间的关联。产前诊断为前置胎盘且有既往剖宫产史的患者应被视为发生植入性胎盘的高危人群。