Department of Maternal Fetal Medicine and Surgery, Hackensack University Medical Center, Hackensack, NJ, USA.
Department of Obstetrics, Gynecology and Women's Health, Rutgers New Jersey Medical School, Newark, NJ, USA.
Acta Obstet Gynecol Scand. 2019 Feb;98(2):183-187. doi: 10.1111/aogs.13478. Epub 2018 Nov 2.
The presence of a previous uterine scar is a strong risk factor for developing abnormally invasive placentation (AIP). We sought to determine whether a short interpregnancy interval predisposes to AIP. We hypothesized that a short interpregnancy interval after a previous cesarean delivery increases the risk of AIP in comparison with a longer interpregnancy interval.
We performed a retrospective cohort study of women with a histological diagnosis of AIP and a history of a previous cesarean section. Women were included in the control group if they had a previous cesarean section with a placenta underlying the previous uterine scar or an anterior previa. The time interval between pregnancy and AIP data was analyzed using the chi-square test and two-tailed Fisher's exact test.
There was no statistical difference in the interpregnancy interval between women who had AIP vs the control group. Gravidity and parity were found to be significantly higher in the women with AIP vs the controls.
These results suggest that a short interpregnancy interval may not increase the risk of developing AIP.
既往子宫瘢痕是异常侵袭性胎盘（AIP）发生的强烈危险因素。我们旨在确定妊娠间隔时间过短是否会导致 AIP。我们假设与较长的妊娠间隔相比，既往剖宫产术后的妊娠间隔时间过短会增加 AIP 的风险。
我们对既往有剖宫产史且有 AIP 组织学诊断史的妇女进行了回顾性队列研究。如果妇女既往有剖宫产史且胎盘附着于既往子宫瘢痕或前置胎盘，则将其纳入对照组。使用卡方检验和双侧 Fisher 确切概率法分析妊娠与 AIP 数据之间的时间间隔。
AIP 组与对照组之间的妊娠间隔时间无统计学差异。AIP 组的孕次和产次明显高于对照组。
这些结果表明，妊娠间隔时间过短可能不会增加发生 AIP 的风险。
