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己烯雌酚对金黄色葡萄球菌各种胞外产物生成的影响。

Effects of diethylstilbestrol on the production of various extracellular products of Staphylococcus aureus.

作者信息

Yotis W

出版信息

Experientia. 1977 Mar 15;33(3):325-6. doi: 10.1007/BF02002807.

DOI:10.1007/BF02002807
PMID:858357
Abstract

The synthetic estrogen diethylstilbestrol at a subinhibitory level of 1.75 microng/ml diminished the production of staphylococcal alpha toxin, coagulase, deoxyribonuclease and penicillinase. Thus, the reported host beneficial effects of diethylstilbestrol may be partially related to its retardive action of certain toxins, or enzymes of S. aureus.

摘要

合成雌激素己烯雌酚在1.75微克/毫升的亚抑制水平下可减少葡萄球菌α毒素、凝固酶、脱氧核糖核酸酶和青霉素酶的产生。因此,已报道的己烯雌酚对宿主的有益作用可能部分与其对金黄色葡萄球菌某些毒素或酶的抑制作用有关。

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Effects of diethylstilbestrol on the production of various extracellular products of Staphylococcus aureus.己烯雌酚对金黄色葡萄球菌各种胞外产物生成的影响。
Experientia. 1977 Mar 15;33(3):325-6. doi: 10.1007/BF02002807.
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Med Microbiol Immunol. 1976 Jun 1;162(2):143-52. doi: 10.1007/BF02121324.
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Microbiol Immunol. 1989;33(12):981-90. doi: 10.1111/j.1348-0421.1989.tb03156.x.

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Antibiotics (Basel). 2025 Apr 14;14(4):402. doi: 10.3390/antibiotics14040402.
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Antibiotic- and hormonally induced alterations in Staphylococcus aureus.抗生素和激素诱导的金黄色葡萄球菌变化。
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本文引用的文献

1
Concentration, partial purification, properties, and nature of staphylocoagulase.葡萄球菌凝固酶的浓度、部分纯化、性质及本质
Yale J Biol Med. 1948 May;20(5):487-501.
2
ANALYSIS BY TRANSDUCTION OF MUTATIONS AFFECTING PENICILLINASE FORMATION IN STAPHYLOCOCCUS AUREUS.通过转导分析影响金黄色葡萄球菌青霉素酶形成的突变
J Gen Microbiol. 1963 Oct;33:121-36. doi: 10.1099/00221287-33-1-121.
3
Isolation and composition of staphylococcal alpha toxin.葡萄球菌α毒素的分离与组成
J Gen Microbiol. 1963 Mar;30:455-68. doi: 10.1099/00221287-30-3-455.
4
Iodometric assay of penicillinase.青霉素酶的碘量法测定
Nature. 1954 Nov 27;174(4439):1012-3. doi: 10.1038/1741012a0.
5
Analytical scanning isoelectrofocusing. 5. Separation of glycinin subunits in urea-dithiothreitol media.分析性扫描等电聚焦。5. 在尿素-二硫苏糖醇介质中大豆球蛋白亚基的分离。
Anal Biochem. 1971 Dec;44(2):436-44. doi: 10.1016/0003-2697(71)90230-2.
6
Mechanism of action of the female sex hormones.女性性激素的作用机制。
Annu Rev Biochem. 1972;41:203-30. doi: 10.1146/annurev.bi.41.070172.001223.
7
Analytical scanning isoelectrofocusing. 3. Design and operation of an in situ scanning apparatus.分析扫描等电聚焦。3. 原位扫描装置的设计与操作。
Anal Biochem. 1971 Dec;44(2):411-26. doi: 10.1016/0003-2697(71)90228-4.
8
Actions of vertebrate sex hormones.脊椎动物性激素的作用。
Annu Rev Physiol. 1971;33:31-82. doi: 10.1146/annurev.ph.33.030171.000335.