McDonald G B, Brand D L, Thorning D R
Gastroenterology. 1977 Jun;72(6):1317-21.
Multiple polypoid masses were found in the esophagus of a 62-year-old man. He underwent esophageal resection because exfoliative and brush cytological studies were positive for adenocarcinoma. The surgical specimen showed that the esophagus was lined by columnar epithelial cells which were focally hyperplastic, forming polypoid masses. In both the masses and the mucosa between them, there were atypical epithelial cell changes, ranging from dysplasia to focal carcinoma. These findings reinforce the concept that the Barrett's (columnar) epithelium is a premalignant lesion deserving periodical screening.
在一名62岁男性的食管中发现了多个息肉样肿物。由于脱落细胞学和刷片细胞学检查腺癌呈阳性，他接受了食管切除术。手术标本显示，食管内衬柱状上皮细胞，这些细胞局灶性增生，形成息肉样肿物。在肿物及其间的黏膜中，均存在非典型上皮细胞改变，从发育异常到局灶性癌。这些发现强化了这样一种观念，即巴雷特（柱状）上皮是一种需要定期筛查的癌前病变。
