Prünte C
University Eye Clinic Basal, Switzerland.
Int Ophthalmol. 1995;19(2):77-82. doi: 10.1007/BF00133176.
There has been great controversy about the pathogenesis of the focal changes in the retinal pigment epithelium (RPE) causing detachment of the neurosensory retina in central serous chorioretinopathy (CSC). This study was performed to evaluate changes in choroidal perfusion in 15 patients with CSC. Fluorescein and indocyanine green (ICG) angiography was performed in patients with acute or chronic recurrent CSC. In all patients delayed arterial filling followed by capillary and/or venous congestion, in some cases adjacent to ischemic areas, was found in the choroid. Leakage from the RPE in fluorescein angiography was only observed in those areas with choroidal capillary and/or venous congestion. The preliminary results suggest that venous congestion possibly in association with ischemia causes hyperpermeability of choroidal vessels already described in the literature.
在中心性浆液性脉络膜视网膜病变（CSC）中，视网膜色素上皮（RPE）的局灶性改变导致神经感觉视网膜脱离的发病机制一直存在很大争议。本研究旨在评估15例CSC患者脉络膜灌注的变化。对急性或慢性复发性CSC患者进行了荧光素和吲哚菁绿（ICG）血管造影。在所有患者中，均发现脉络膜存在动脉充盈延迟，随后出现毛细血管和/或静脉充血，在某些情况下与缺血区域相邻。荧光素血管造影中RPE渗漏仅在脉络膜毛细血管和/或静脉充血的区域观察到。初步结果表明，可能与缺血相关的静脉充血导致了文献中已描述的脉络膜血管高渗透性。
