Lekili M, Minareci S, Nergis N, Serim U, Ayder A R
Department of Urology, SSK Buca Hospital, Izmir, Turkey.
Int Urol Nephrol. 1995;27(4):423-9. doi: 10.1007/BF02550078.
Thirty consecutive patients with germinal testis tumours were treated with combined-modality programme. Seven patients were entered in the surveillance protocol, 7 patients had irradiation of the paraaortic and ipsilateral pelvic lymph nodes, 16 patients were treated with four courses of chemotherapy. Of the patients 5 underwent surgical removal of residual masses. After the combined-modality treatment 27 (90%) patients had complete remission, 2 patients showed progression on therapy and the other had incomplete resection of residual masses. After a median follow-up period of 41.5 months, 27 (90%) remain continuously disease-free, 2 patients died and one patient is still alive with his enlarged mediastinal lymph nodes. The treatment policy stage by stage was defined by the current roles of surgery, irradiation and chemotherapy in our efforts.
连续30例原发性睾丸肿瘤患者接受了综合治疗方案。7例患者进入监测方案,7例患者接受了腹主动脉旁及同侧盆腔淋巴结照射,16例患者接受了四个疗程的化疗。其中5例患者接受了残留肿块的手术切除。综合治疗后,27例(90%)患者完全缓解,2例患者在治疗过程中病情进展,另1例患者残留肿块切除不完全。中位随访41.5个月后,27例(90%)患者持续无病生存,2例患者死亡,1例患者纵隔淋巴结肿大仍存活。我们根据手术、放疗和化疗在当前治疗中的作用,逐步确定了治疗策略。