Wishnow K I, Johnson D E, Tenney D
Department of Urology, University of Texas M. D. Anderson Cancer Center, Houston 77030.
J Urol. 1989 May;141(5):1133-5. doi: 10.1016/s0022-5347(17)41191-8.
Lymphangiographic findings in 174 patients with early stage nonseminomatous testicular tumors were evaluated retrospectively to determine the need to perform the procedure before patients are placed on surveillance. When physical examination, chest x-ray, computerized tomographic scans and serum tumor marker levels were normal, lymphangiography detected unsuspected metastasis in only 4 per cent of the patients, while providing misinformation in another 4 per cent. Plain radiographs of 99 patients on surveillance taken at 2-month intervals resulted in only 1 instance when the x-rays became positive and were the first evidence of metastasis. These findings indicate that routine lymphangiography is not necessary to assess the retroperitoneum when computerized tomography and the serum tumor markers are unequivocally normal.
对174例早期非精原细胞瘤性睾丸肿瘤患者的淋巴管造影结果进行回顾性评估,以确定在患者进入监测之前进行该检查的必要性。当体格检查、胸部X线、计算机断层扫描和血清肿瘤标志物水平均正常时,淋巴管造影仅在4%的患者中检测到意外转移,同时在另外4%的患者中提供了错误信息。对99例接受监测的患者每隔2个月进行的X线平片检查,仅出现1例X线呈阳性且为转移的首个证据的情况。这些结果表明,当计算机断层扫描和血清肿瘤标志物明确正常时,常规淋巴管造影对于评估腹膜后情况并非必要。