单纯皮肤型罗萨伊-多夫曼病

Purely cutaneous Rosai-Dorfman disease.

作者信息

Skiljo M, García-Lora E, Tercedor J, Massare E, Esquivias J, García-Mellado V

机构信息

Department of Dermatology, Hospital Virgen de las Nieves, Granada, Spain.

出版信息

Dermatology. 1995;191(1):49-51. doi: 10.1159/000246488.

DOI:10.1159/000246488

PMID:8589484

Abstract

Sinus histiocytosis with massive lymphadenopathy is an entity that exceptionally appears as a purely cutaneous disease. We described 2 cases of this form with spontaneous involution. Histology showed a polymorphic infiltrate in the dermis and hypodermis composed of large histiocytes with lymphophagocytosis, neutrophils and plasma cells. Immunohistochemical stains demonstrated the positivity of histiocytes for protein S-100 and MAC 387.

摘要

伴巨大淋巴结病的窦性组织细胞增生症是一种罕见地表现为单纯皮肤疾病的实体。我们描述了2例这种自发消退形式的病例。组织学显示真皮和皮下组织有由具有噬淋巴细胞现象的大组织细胞、中性粒细胞和浆细胞组成的多形性浸润。免疫组织化学染色显示组织细胞对蛋白质S-100和MAC 387呈阳性。