Fasman K H, Letovsky S I, Cottingham R W, Kingsbury D T
Division of Biomedical Information Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Nucleic Acids Res. 1996 Jan 1;24(1):57-63. doi: 10.1093/nar/24.1.57.
Version 6.0 of the Human Genome Data Base introduces a number of significant improvements over previous releases of GDB. The most important of these are revised data representations for genes and genomic maps and a new curatorial model for the database. GDB 6.0 is the first major genomic database to provide read/write access directly to the scientific community, including capabilities for third-party annotation. The revised database can represent all major categories of genetic and physical maps, along with the underlying order and distance information used to construct them. The improved representation permits more sophisticated map queries to be posed and supports the graphical display of maps. In addition the new GDB has a richer model for gene information, better suited for supporting cross-references to databases describing gene function, structure, products, expression and associated phenotypes.
人类基因组数据库6.0版本相比GDB之前的版本有许多重大改进。其中最重要的是对基因和基因组图谱的数据表示进行了修订,以及数据库采用了新的管理模型。GDB 6.0是第一个直接向科学界提供读/写访问权限的主要基因组数据库,包括第三方注释功能。修订后的数据库可以表示所有主要类型的遗传图谱和物理图谱,以及用于构建这些图谱的基础顺序和距离信息。改进后的表示方式允许提出更复杂的图谱查询,并支持图谱的图形显示。此外,新的GDB拥有更丰富的基因信息模型,更适合支持与描述基因功能、结构、产物、表达及相关表型的数据库进行交叉引用。