人乳头瘤病毒感染与宫颈上皮异常进展风险
Human papillomavirus infection and risk of progression of epithelial abnormalities of the cervix.
作者信息
Woodman C B, Rollason T, Ellis J, Tierney R, Wilson S, Young L
机构信息
Centre for Cancer Epidemiology, Christie Hospital NHS Trust, Manchester, UK.
出版信息
Br J Cancer. 1996 Feb;73(4):553-6. doi: 10.1038/bjc.1996.96.
Abstract
The polymerase chain reaction has been used to determine the presence of human papillomavirus (HPV) 16 and HPV 18 DNA sequences in archival histological material removed from a cohort of untreated women with cervical epithelial abnormalities. The detection of HPV 16 or HPV 18 DNA sequences in the initial biopsy specimen was associated with a significantly increased risk of subsequent disease progression.
摘要
聚合酶链反应已被用于确定从一组未经治疗的宫颈上皮异常女性身上获取的存档组织学材料中是否存在人乳头瘤病毒（HPV）16和HPV 18 DNA序列。在初始活检标本中检测到HPV 16或HPV 18 DNA序列与随后疾病进展风险的显著增加相关。
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