Cavaillolès F, Bazin J P, Pavel D, Olea E, Faraggi M, Frouin F, Di Paola R
Clinique des Hauts de Seine, Chatenay-Malabry, France.
Int J Card Imaging. 1995 Dec;11(4):263-72. doi: 10.1007/BF01145195.
To evaluate Factor Analysis of Dynamic Structures (FADS) versus or in association with other methods, a protocol was set up including as 'gold standard' investigation the left ventricular angiography (LVA) and processing by Fourier Analysis (FA), and FADS with different variants. To refine the diagnosis of Regional Wall Motion Abnormalities (RWMA), processing was done on a sectorial basis for more accurate spatial localization and functional description. 53 patients were studied (8 normal, 45 with coronary artery disease). FADS gave better results than FA on a sectorial basis. Total agreement between FADS and LVA was obtained in 208/265 (78%), while FA was in agreement with LVA in only 167/265 segments (63%). Globally, FADS was significantly better than FA (Z-test: p < 0.05). When only the diagnosis of maximal abnormality was considered, FA and FADS are statistically equivalent. The superiority of FADS vs FA is more obvious in the diagnosis of hypokinesia. Most FA discrepancies corresponded to underestimation of WMA.
为了评估动态结构因子分析（FADS）与其他方法相比或与之联合使用的情况，制定了一项方案，其中包括将左心室血管造影（LVA）和傅里叶分析（FA）处理作为“金标准”研究，以及不同变体的FADS。为了完善局部室壁运动异常（RWMA）的诊断，对扇形区域进行处理以实现更准确的空间定位和功能描述。研究了53例患者（8例正常，45例患有冠状动脉疾病）。在扇形区域基础上，FADS比FA给出了更好的结果。FADS与LVA之间的完全一致性在208/265个节段中获得（78%），而FA仅在167/265个节段中与LVA一致（63%）。总体而言，FADS明显优于FA（Z检验：p<0.05）。仅考虑最大异常的诊断时，FA和FADS在统计学上等效。FADS相对于FA的优越性在运动减退的诊断中更为明显。大多数FA差异对应于对室壁运动异常的低估。
