Roncaroli F, Eusebi V
Institute of Anatomic Pathology, University of Bologna, Italy.
Hum Pathol. 1996 Mar;27(3):310-3. doi: 10.1016/s0046-8177(96)90075-1.
A case of leiomyosarcoma of the retroperitoneum with rhabdomyoblastic areas which developed in a 59-year-old woman is reported. The tumor was composed mostly of spindle cells immunoreactive with desmin and smooth muscle actin antisera. In the lesion there were no fewer than five patches constituted by large pleomorphic elements which reacted with antidesmin, sarcomeric actin and myoglobin antisera. These dual features were interpreted as the result of a divergent differentiation of neoplastic cells.
报告了一例发生在一名59岁女性身上的伴有横纹肌母细胞区域的腹膜后平滑肌肉瘤。肿瘤主要由与结蛋白和平滑肌肌动蛋白抗血清呈免疫反应的梭形细胞组成。在病变中，有不少于五个由大的多形性成分构成的区域，这些成分与抗结蛋白、肌节肌动蛋白和肌红蛋白抗血清发生反应。这些双重特征被解释为肿瘤细胞分化异常的结果。
