Sugg M J, Polich J
Department of Neuropharmacology TPC-10, Scripps Research Institute, La Jolla, CA 92037, USA.
Biol Psychol. 1995 Nov 16;41(3):255-69. doi: 10.1016/0301-0511(95)05136-8.
Auditory stimulus intensity (45, 60, 75 dB SPL) and standard/target frequency (250/500) and 1000/2000 Hz) were manipulated factorially to assess their effects on the P3(00) event-related brain potential (ERP). For the target stimuli, intensity increases produced reliable increases in P3 amplitude and decreases in peak latency. P3 latency at the lowest intensity level was marginally longer for the low frequency condition. For the standard stimuli, intensity increases produced reliable P3 amplitude increases, low frequency stimuli yielded smaller components than high frequency stimuli, and several interactions with the electrode factor were obtained. P3 latency decreased as intensity increased, and low frequency tones produced longer latencies than high frequency tones. The N1, P2, and N2 components from both stimulus types generally were affected in the same manner: intensity increases producing larger amplitudes and shorter latencies, with some effects of tone frequency also observed. The findings suggest that auditory stimulus parameters contribute to both P3 amplitude and latency measures in important ways and are discussed in relation to the use of ERPs in applied contexts.
对听觉刺激强度（45、60、75分贝声压级）以及标准/目标频率（250/500和1000/2000赫兹）进行析因处理，以评估它们对P3（00）事件相关脑电位（ERP）的影响。对于目标刺激，强度增加会使P3波幅可靠增加，峰潜伏期缩短。在最低强度水平下，低频条件下的P3潜伏期略长。对于标准刺激，强度增加会使P3波幅可靠增加，低频刺激产生的成分比高频刺激小，并且获得了与电极因素的几种相互作用。P3潜伏期随强度增加而缩短，低频音产生的潜伏期比高频音长。两种刺激类型的N1、P2和N2成分通常以相同方式受到影响：强度增加会产生更大的波幅和更短的潜伏期，同时也观察到了音调频率的一些影响。研究结果表明，听觉刺激参数在重要方面对P3波幅和潜伏期测量都有贡献，并结合ERP在应用情境中的使用进行了讨论。
