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对神经功能受损成年患者的肝脾损伤进行选择性非手术治疗。

Selective nonoperative management of liver and spleen injuries in neurologically impaired adult patients.

作者信息

Archer L P, Rogers F B, Shackford S R

机构信息

Department of Surgery, National Naval Medical Center, Bethesda, Maryland, USA.

出版信息

Arch Surg. 1996 Mar;131(3):309-15. doi: 10.1001/archsurg.1996.01430150087017.

Abstract

BACKGROUND

Nonoperative management of blunt liver and spleen injuries in hemodynamically stable, neurologically intact patients has become an accepted treatment in recent years.

OBJECTIVE

To determine the morbidity and mortality in neurologically impaired adult patients who had sustained blunt liver or spleen injuries and who had been managed nonoperatively in a monitored setting, owing to the preponderance of blunt trauma and associated head injuries in Vermont.

DESIGN

Case-control study.

SETTING

Regional level I trauma center in northern Vermont.

PATIENTS

One hundred eighty-seven consecutive patients with documented blunt splenic or hepatic trauma who were admitted to a regional rural trauma referral center in Vermont during an 8-year period, beginning in January 1987, were studied. Hemodynamically stable patients underwent diagnostic imaging studies and were classified by mental status as either normal or altered. Patients who required operative intervention were excluded.

MAIN OUTCOME MEASURES

Morbidity and mortality rates for each group were recorded and compared to determine if statistically significant differences between the two groups existed.

RESULTS

The groups were similar in age, systolic blood pressure, and hematocrit at admission. The group of patients with an altered mental status were more severely injured and had a longer hospital stay. Intensive care unit stays were not significantly different. Transfusion requirements for both groups were minimal; however, the group of patients with an altered mental status received more blood transfusions compared with the group of patients with a normal mental status. There was no significant difference in morbidity and mortality between the two groups. There were no failures of nonoperative management, no complications, and no missed visceral injuries in the group of patients with an altered mental status. Patients older than 50 years had higher morbidity and mortality.

CONCLUSIONS

Nonoperative management in patients with an altered mental status can be done safely in a monitored setting. This challenges the current criteria of excluding neurologically impaired patients with liver or spleen trauma from nonoperative management.

摘要

背景

近年来,对于血流动力学稳定、神经功能正常的钝性肝脾损伤患者,非手术治疗已成为一种被认可的治疗方法。

目的

鉴于佛蒙特州钝性创伤和相关头部损伤的普遍性,确定因钝性肝或脾损伤而在监测环境中接受非手术治疗的神经功能受损成年患者的发病率和死亡率。

设计

病例对照研究。

地点

佛蒙特州北部的一级区域创伤中心。

患者

对1987年1月开始的8年期间连续收治到佛蒙特州一家区域农村创伤转诊中心的187例有记录的钝性脾或肝创伤患者进行了研究。血流动力学稳定的患者接受了诊断性影像学检查,并根据精神状态分为正常或异常。需要手术干预的患者被排除在外。

主要观察指标

记录并比较每组的发病率和死亡率,以确定两组之间是否存在统计学上的显著差异。

结果

两组患者入院时的年龄、收缩压和血细胞比容相似。精神状态异常的患者受伤更严重,住院时间更长。重症监护病房的住院时间无显著差异。两组的输血需求都很少;然而,与精神状态正常的患者组相比,精神状态异常的患者组接受的输血更多。两组之间的发病率和死亡率无显著差异。精神状态异常的患者组中没有非手术治疗失败、没有并发症、也没有漏诊的内脏损伤。50岁以上的患者发病率和死亡率更高。

结论

在监测环境中,对精神状态异常的患者进行非手术治疗是安全的。这对目前将肝脾创伤的神经功能受损患者排除在非手术治疗之外的标准提出了挑战。

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